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Keep track of Closely (3)pentobarbital will lower the level or outcome of diazepam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Sturdy or moderate CYP3A4 inducers may perhaps raise charge of diazepam elimination; consequently, efficacy of diazepam could possibly be diminished.pentobarbital will lower the l